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A process for preparing 2-amino-6-chloropurine comprises reacting a 29-diacylated derivative of guanine with a chlorinating agent in the presence of a phase transfer catalyst containing chloride ions and thereafter removing the 9-acyl group and the 2-acyl group by hydrolysis. Melting Point 300 Clit MSDS.
Instead imidazoles 5a b were isolated in high yields from these reactions.
2 amino 6 chloropurine. Annons Aminosyror till Sveriges bästa priser. Ta dig igenom ditt träningspass med hjälp av våra hög kvalitet aminosyror. 2-Amino-6-chloropurine is a 6-substituted purine.
Tautomeric purine forms of 2-amino-6-chloropurine were investigated by vibrational spectroscopy and quantum chemical method. Application 2-Amino-6-chloropurine may be used. In the enzymatic synthesis of 2-deoxyguanosine.
7 rader 2-Amino-6-chloropurine 99 Synonym. 6-Chloro-2-purinamine 6-Chloroguanine CAS Number. 2-Amino-6-chloropurine finds its uses in the enzymatic synthesis of 2-deoxyguanosine 9-alkyl purines and R- and S-N-2-phosphonomethoxypropyl derivatives of purine and pyrimidine bases.
Notes Store away from oxidizing agents. Shop a large selection of Halopyrimidines products and learn more about 2-Amino-6-chloropurine 99 ACROS Organics 5g. Glass bottle 2-Amino-6-chloropurine 99.
Shop 2-Amino-6-chloropurine 99 ACROS Organics at Fisherscise. Antibodies Protein Biology. 2-Amino-6-chloropurine CAS Number.
C 5 H 4 ClN 5. Melting Point 300 Clit MSDS. No starting material was recovered when 2-amino-6-chloropurine 3a was treated with an excess of LDA and the reaction quenched with water Table 1 entry 1.
Likewise addition of C 2 Cl 6 to the purine-LDA mixture did not lead to the 8-chloro derivative 4a. Instead imidazoles 5a b were isolated in high yields from these reactions. PURINE 2-AMINO-6-CHLORO- 9H-PURINE 2-AMINO-6-CHLORO- 1H-Purin-2-amine 6-chloro-.
26-Diaminopurine hemisulfate salt hydrate. 9-4-Acetoxy-3-acetoxymethylbut-1-yl-2-amino-6-chloropurine C14H18ClN5O4 CID 10155164 - structure chemical names physical and chemical properties classification patents literature biological activities safetyhazardstoxicity information supplier lists and more. 2-Amino-6-chloropurine riboside 95.
Mode of action of 2-amino-6-chloro-1-deazapurine. Bennett LL Jr Smithers D Rose LM Adamson DJ Brockman RW Biochem Pharmacol 1984 Jan 15332261-71. A process for preparing 2-amino-6-chloropurine comprises reacting a 29-diacylated derivative of guanine with a chlorinating agent in the presence of a phase transfer catalyst containing chloride ions and thereafter removing the 9-acyl group and the 2-acyl group by hydrolysis.
Inspired by the work reported by Dey Garner 2000 on the synthesis of tris-tert-butoxycarbonyl 2-amino-6-chloropurine we decided to employ a similar strategy for preparing these monomers. As had been found by Dey Garner 2000 this reaction afforded a single product. Copyright 2017-2020 Sigma-Aldrich Co.
- Database Compilation Copyright 2017-2020 John Wiley Sons Inc. Synthesis of 6-deoxycyclopropavir 10 a prodrug of cyclopropavir 1 and its in vitro and in vivo antiviral activity is described. 2-Amino-6-chloropurine methylenecyclopropane 13 was transformed to its 6-iodo derivative 14 which was reduced to prodrug 10.
Annons Aminosyror till Sveriges bästa priser. Ta dig igenom ditt träningspass med hjälp av våra hög kvalitet aminosyror.