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CLASSIFICATION OF ANTINEOPLASTIC AGENTS There are two Major Groups of Anticancer Drugs. MOPP Hodgkins leukemia lymphosarcoma AE.
Classification According to chemical structure and sources of drugs.
Anticancer drugs classification ppt. Anticancer drugs 1 introduction and classification. Parasuraman Faculty of Pharmacy AIMST. Anticancer drugs The anticancer drug either kill cancer cells or modify their growth.
Discovery of anticancer agents started after 1940s when. Cellular Pathways to. MOPP Hodgkins leukemia lymphosarcoma AE.
Myelosuppression Leukopenia Thrombocytopenia Nausea and vomiting Extravasation. Carmustine Lomustine Semustine MOA. Chloro ethyl moiety- capable of alkylating nucleic acids and proteins Alkylation and Carbamoylation of DNA.
CLASSIFICATION OF ANTINEOPLASTIC AGENTS There are two Major Groups of Anticancer Drugs. CHEMICAL STRUCTURE AND RESOURCE OF THE DRUG A Cytotoxic Drugs largest group -Alkylating agents -Antimetabolites -Antitumor antibiotics - Plant-derived products -Miscellaneous cytotoxic drugs B Hormones and hormone antagonists C Immunomodulators. Classification According to chemical structure and sources of drugs.
Alkylating Agents Antimetabolite Antibiotics Plant Extracts Hormones and Others According to biochemical mechanisms of anticancer action. Block nucleic acid biosynthesis Direct influence the structure and function of DNA Interfere transcription and block RNA synthesis Interfere protein synthesis and function Influence hormone homeostasis According to the cycle or phase specificity of the drug. Classification of anticancer drugs Cell cyclespecific CCS drugs.
Acts on proliferating cells are most effective in hematologic malignancies and in solid tumors in which a relatively large proportion of the cells are proliferating Cell cyclenonspecific CCNS drugs. Can kill both G0 and cycling cells although cycling cells are more sensitive. Anticancer Drugs Market Research Report 2018 - In this report the global Anticancer Drugs market is valued at USD XX million in 2017 and is expected to reach USD XX million by the end of 2025.
The PowerPoint PPT presentation. Classification of Drugs is the property of its rightful owner. CLASSIFICATION OF CYTOTOXIC AGENTS BUSULFAN CYTOSINE ETOPOSIDE BLEOMYCIN L-ASPARAGINASE CARMUSTINE ARABINOSIDE TAXOIDS DACTINOMYCIN HYDROXYUREA CHLORAMBUCIL FLOXURIDINE VINBLASTINE DAUNORUBICIN PROCARBAZINE CISPLATIN FLUOROURACIL VINCRISTINE DOXORUBICIN CYCLOPHOSPHAMIDE.
Newer anticancer drugs Inhibitors of growth factors receptors Imatinib. CML BCR-ABL gene Gefitinib. Non small cell cancer of lungs EGFR Nilotinib.
CML Tyrosine kinase inhibitor Dasatinib. CML Tyrosine kinase inhibitor Lapatinib. Metastatic breast cancer HER2neu Sunitinib.
Renal cell carcinoma VEGF Sorafinib. Renal cell carcinoma VEGF. Top 10 anti cancer drugs.
Anti cancer drugs list ppt pharmacology. List of anti cancer drugs alkylating agents. Busulfan carmustine bcnu cyclophosphamide dacarbazine lomustine ccnu mechlorethamine melphalan thiotepa.
Bleomycin dactinomycin daunorubicin doxorubicin etoposide vp-16 irinotecan mitomycin c paclitaxel vinblastine vincristine. The arrival of a great number of new antineoplastic agents has made it necessary to reclassify all of them. Anticancer drugs may act at different levels.
Anticancer Drugs Market Research Report 2018 - In this report the global Anticancer Drugs market is valued at USD XX million in 2017 and is expected to reach USD XX million by the end of 2025 growing at a CAGR of XX between 2017 and 2025. PowerPoint PPT presentation free to view. Drug therapy may be used alone or in combination with other treatments such as surgery or radiation therapy.
Anti cancer drugs kill the cancer cell by first order kinetic means concentration dependent killing is done by Anti cancer drugs. For complete cure of cancer all cancerous cells must be killed as single cell capable of producing cancer. Indications for use Lympho- and myeloblastic leukosis neuroleukemia myelomatosis trophoblastomas uterine chorioepithelioma cystic mole incl.
Invasive mole esophageal cancer epidermoid cancer of head and neck cancer of urinary bladder cancer of lung liver cancer. J Codes For Chemotherapy Drugs 2020 - Chemotherapy administration services. CPT codes 96400 96408 to 96425 96520 and 96530 Therapeutic or diagnostic infusions excluding chemotherapy.
CPT codes 90780 to 90781 Drug injection codes 90782 to 90788 are paid under the Medicare physician fee schedule. For chemotherapy administration services furnished prior to January 1 2004 the carrier. ANTINEOPLASTIC AGENT GOAL OF TREATMENT.
TYPES OF AGENT to treat cancer cells and Cell cycle specific. Conserve normal cells by respond during a specific interfering with cancer cycle of the cell cell reproduction Cell cycle non-specific. USE respond during any Cure phase Relieve symptoms Recovery period is Prevent complication needed to.
Cancer drugs can be divided into two general classes. CELL CYCLE SPECIFIC DRUGS CCS. Plant alkaloids and antimetabolites and CELL CYCLE NON-SPECIFIC DRUGS CCNS.
Alkylating agents and some natural. Chemotherapy in cancer commonly involves the use of drug combinations to enhance antitumor actions and to prevent development of resistance. The ABVD regimen includes doxorubicin Adriamycin bleomycin vinblastine and dacarbazine an alkylating agent.
2 types of Anti cancer drugs 1. CCNS Cell cycle non specific drugs Alkylating drugs Anti tumor antibiotic Nitrosureas Steroids CCS Cell cycle Specific Drugs Antimetabolites Alkaloids some anti tumor antibiotic Adverse Reaction to anti cancer drugs. Bone marrow suppression Low WBC susceptibility to infection with a decreased WBC count.
Natural Herbs as Anti cancer Drugs Nidhi Agarwal 1 Chandana Majee 1 G. Chakraborth y 1 1 Department of Pharmaceutical Technology Noida Institute of Engineering.